XenakisV1, France, Analysis, bibRecord, 000016

Biocompatible nanodispersions as delivery systems of food additives: A structural study

Identifieur interne : 000016 ( France/Analysis ); précédent : 000015; suivant : 000017

Biocompatible nanodispersions as delivery systems of food additives: A structural study

Auteurs : Argyro Kalaitzaki [Grèce] ; Melanie Emo [France] ; Marie José Stebe [France] ; Aristotelis Xenakis [Grèce] ; Vassiliki Papadimitriou [Grèce]

Source :

Food Research International [ 0963-9969 ] ; 2013-12.

RBID : Hal:hal-01493933

English descriptors

mix :
- DLS, EPR, Gallic acid, SAXS, Squalene, O/w microemulsions.

Abstract

Nanodispersions based on food grade biocompatible materials were developed and structurally characterized to be used as carriers of bioactive compounds with specific nutritional value. The main idea was to formulate concentrated solutions of specific food components at the nanoscale to be consumed either on their own or as integrating parts of classic foods, upon aqueous dilution. For this purpose microemulsions consisting of (R)-(+)-limonene/ethanol/Tween 40/water/propylene glycol were formulated in the presence and in the absence of squalene, gallic acid and octyl gallate. The limits of the single-phase region as described by pseudo-ternary phase diagrams were related to the nature of the food additive. The more extended monophasic region was obtained when octyl gallate was added in the system. Interfacial properties of the microemulsions were studied by electron paramagnetic resonance (EPR) spectroscopy employing the nitroxide spin probe 5-doxylstearic acid (5-DSA). In general guest molecules decreased the flexibility of the surfactant monolayer as manifested from the calculation of rotational correlation time (T-R) and order parameter S of 5-DSA. Particle size measurements were performed using dynamic light scattering (DLS) and oil droplet diameters in the range of 11.7 to 17.4 nm were observed. The addition of squalene resulted in the formulation of larger oily droplets whereas octyl gallate formed smaller ones. Finally SAXS experiments provided qualitative information of o/w microemulsions showing squalene solubilization in the dispersed oily phase, octyl gallate localization on the membrane and gallic acid solubilization in the continuous aqueous phase.

Url:

https://hal.univ-lorraine.fr/hal-01493933

DOI: 10.1016/j.foodres.2013.08.010

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000006
to stream Hal, to step Curation: 000006
to stream Hal, to step Checkpoint: 000017
to stream Main, to step Merge: 000030
to stream Main, to step Curation: 000029
to stream Main, to step Exploration: 000029
to stream France, to step Extraction: 000016

Links to Exploration step

Hal:hal-01493933

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Biocompatible nanodispersions as delivery systems of food additives: A structural study</title>
<author><name sortKey="Kalaitzaki, Argyro" sort="Kalaitzaki, Argyro" uniqKey="Kalaitzaki A" first="Argyro" last="Kalaitzaki">Argyro Kalaitzaki</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-469482" status="VALID">          <orgName>National Hellenic Research Foundation [Athens]</orgName>
          <date type="start">2016-10-21</date>
          <desc>            <address>              <country key="GR"></country>
            </address>
          </desc>
        </hal:affiliation>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Emo, Melanie" sort="Emo, Melanie" uniqKey="Emo M" first="Melanie" last="Emo">Melanie Emo</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-162285" status="OLD">          <idno type="IdUnivLorraine">[UL]RPH--</idno>
          <idno type="RNSR">199712611A</idno>
          <idno type="IdRef">166895385</idno>
          <orgName>Structure et Réactivité des Systèmes Moléculaires Complexes</orgName>
          <orgName type="acronym">SRSMC</orgName>
          <date type="start">2012-01-01</date>
          <date type="end">2017-12-31</date>
          <desc>            <address>              <addrLine>Université de Lorraine, Faculté des Sciences et Techniques, BP 70239, 54506 Vandoeuvre les Nancy Cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.srsmc.univ-lorraine.fr/</ref>
          </desc>
          <listRelation>            <relation active="#struct-413289" type="direct"></relation>
            <relation name="UMR7565" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID">          <idno type="IdRef">157040569</idno>
          <idno type="IdUnivLorraine">[UL]100--</idno>
          <orgName>Université de Lorraine</orgName>
          <orgName type="acronym">UL</orgName>
          <date type="start">2012-01-01</date>
          <desc>            <address>              <addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.univ-lorraine.fr/</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR7565" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="ISNI">0000000122597504</idno>
          <idno type="IdRef">02636817X</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
<placeName><settlement type="city">Nancy</settlement>
<settlement type="city">Metz</settlement>
<region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
</placeName>
<orgName type="university">Université de Lorraine</orgName>
</affiliation>
</author>
<author><name sortKey="Stebe, Marie Jose" sort="Stebe, Marie Jose" uniqKey="Stebe M" first="Marie José" last="Stebe">Marie José Stebe</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-162285" status="OLD">          <idno type="IdUnivLorraine">[UL]RPH--</idno>
          <idno type="RNSR">199712611A</idno>
          <idno type="IdRef">166895385</idno>
          <orgName>Structure et Réactivité des Systèmes Moléculaires Complexes</orgName>
          <orgName type="acronym">SRSMC</orgName>
          <date type="start">2012-01-01</date>
          <date type="end">2017-12-31</date>
          <desc>            <address>              <addrLine>Université de Lorraine, Faculté des Sciences et Techniques, BP 70239, 54506 Vandoeuvre les Nancy Cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.srsmc.univ-lorraine.fr/</ref>
          </desc>
          <listRelation>            <relation active="#struct-413289" type="direct"></relation>
            <relation name="UMR7565" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID">          <idno type="IdRef">157040569</idno>
          <idno type="IdUnivLorraine">[UL]100--</idno>
          <orgName>Université de Lorraine</orgName>
          <orgName type="acronym">UL</orgName>
          <date type="start">2012-01-01</date>
          <desc>            <address>              <addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.univ-lorraine.fr/</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR7565" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="ISNI">0000000122597504</idno>
          <idno type="IdRef">02636817X</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
<placeName><settlement type="city">Nancy</settlement>
<settlement type="city">Metz</settlement>
<region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
</placeName>
<orgName type="university">Université de Lorraine</orgName>
</affiliation>
</author>
<author><name sortKey="Xenakis, Aristotelis" sort="Xenakis, Aristotelis" uniqKey="Xenakis A" first="Aristotelis" last="Xenakis">Aristotelis Xenakis</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-469482" status="VALID">          <orgName>National Hellenic Research Foundation [Athens]</orgName>
          <date type="start">2016-10-21</date>
          <desc>            <address>              <country key="GR"></country>
            </address>
          </desc>
        </hal:affiliation>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Papadimitriou, Vassiliki" sort="Papadimitriou, Vassiliki" uniqKey="Papadimitriou V" first="Vassiliki" last="Papadimitriou">Vassiliki Papadimitriou</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-469482" status="VALID">          <orgName>National Hellenic Research Foundation [Athens]</orgName>
          <date type="start">2016-10-21</date>
          <desc>            <address>              <country key="GR"></country>
            </address>
          </desc>
        </hal:affiliation>
<country>Grèce</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-01493933</idno>
<idno type="halId">hal-01493933</idno>
<idno type="halUri">https://hal.univ-lorraine.fr/hal-01493933</idno>
<idno type="url">https://hal.univ-lorraine.fr/hal-01493933</idno>
<idno type="doi">10.1016/j.foodres.2013.08.010</idno>
<date when="2013-12">2013-12</date>
<idno type="wicri:Area/Hal/Corpus">000006</idno>
<idno type="wicri:Area/Hal/Curation">000006</idno>
<idno type="wicri:Area/Hal/Checkpoint">000017</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000017</idno>
<idno type="wicri:doubleKey">0963-9969:2013:Kalaitzaki A:biocompatible:nanodispersions:as</idno>
<idno type="wicri:Area/Main/Merge">000030</idno>
<idno type="wicri:Area/Main/Curation">000029</idno>
<idno type="wicri:Area/Main/Exploration">000029</idno>
<idno type="wicri:Area/France/Extraction">000016</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Biocompatible nanodispersions as delivery systems of food additives: A structural study</title>
<author><name sortKey="Kalaitzaki, Argyro" sort="Kalaitzaki, Argyro" uniqKey="Kalaitzaki A" first="Argyro" last="Kalaitzaki">Argyro Kalaitzaki</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-469482" status="VALID">          <orgName>National Hellenic Research Foundation [Athens]</orgName>
          <date type="start">2016-10-21</date>
          <desc>            <address>              <country key="GR"></country>
            </address>
          </desc>
        </hal:affiliation>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Emo, Melanie" sort="Emo, Melanie" uniqKey="Emo M" first="Melanie" last="Emo">Melanie Emo</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-162285" status="OLD">          <idno type="IdUnivLorraine">[UL]RPH--</idno>
          <idno type="RNSR">199712611A</idno>
          <idno type="IdRef">166895385</idno>
          <orgName>Structure et Réactivité des Systèmes Moléculaires Complexes</orgName>
          <orgName type="acronym">SRSMC</orgName>
          <date type="start">2012-01-01</date>
          <date type="end">2017-12-31</date>
          <desc>            <address>              <addrLine>Université de Lorraine, Faculté des Sciences et Techniques, BP 70239, 54506 Vandoeuvre les Nancy Cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.srsmc.univ-lorraine.fr/</ref>
          </desc>
          <listRelation>            <relation active="#struct-413289" type="direct"></relation>
            <relation name="UMR7565" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID">          <idno type="IdRef">157040569</idno>
          <idno type="IdUnivLorraine">[UL]100--</idno>
          <orgName>Université de Lorraine</orgName>
          <orgName type="acronym">UL</orgName>
          <date type="start">2012-01-01</date>
          <desc>            <address>              <addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.univ-lorraine.fr/</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR7565" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="ISNI">0000000122597504</idno>
          <idno type="IdRef">02636817X</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
<placeName><settlement type="city">Nancy</settlement>
<settlement type="city">Metz</settlement>
<region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
</placeName>
<orgName type="university">Université de Lorraine</orgName>
</affiliation>
</author>
<author><name sortKey="Stebe, Marie Jose" sort="Stebe, Marie Jose" uniqKey="Stebe M" first="Marie José" last="Stebe">Marie José Stebe</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-162285" status="OLD">          <idno type="IdUnivLorraine">[UL]RPH--</idno>
          <idno type="RNSR">199712611A</idno>
          <idno type="IdRef">166895385</idno>
          <orgName>Structure et Réactivité des Systèmes Moléculaires Complexes</orgName>
          <orgName type="acronym">SRSMC</orgName>
          <date type="start">2012-01-01</date>
          <date type="end">2017-12-31</date>
          <desc>            <address>              <addrLine>Université de Lorraine, Faculté des Sciences et Techniques, BP 70239, 54506 Vandoeuvre les Nancy Cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.srsmc.univ-lorraine.fr/</ref>
          </desc>
          <listRelation>            <relation active="#struct-413289" type="direct"></relation>
            <relation name="UMR7565" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID">          <idno type="IdRef">157040569</idno>
          <idno type="IdUnivLorraine">[UL]100--</idno>
          <orgName>Université de Lorraine</orgName>
          <orgName type="acronym">UL</orgName>
          <date type="start">2012-01-01</date>
          <desc>            <address>              <addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.univ-lorraine.fr/</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR7565" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="ISNI">0000000122597504</idno>
          <idno type="IdRef">02636817X</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
<placeName><settlement type="city">Nancy</settlement>
<settlement type="city">Metz</settlement>
<region type="region" nuts="2">Grand Est</region>
<region type="old region" nuts="2">Lorraine (région)</region>
</placeName>
<orgName type="university">Université de Lorraine</orgName>
</affiliation>
</author>
<author><name sortKey="Xenakis, Aristotelis" sort="Xenakis, Aristotelis" uniqKey="Xenakis A" first="Aristotelis" last="Xenakis">Aristotelis Xenakis</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-469482" status="VALID">          <orgName>National Hellenic Research Foundation [Athens]</orgName>
          <date type="start">2016-10-21</date>
          <desc>            <address>              <country key="GR"></country>
            </address>
          </desc>
        </hal:affiliation>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Papadimitriou, Vassiliki" sort="Papadimitriou, Vassiliki" uniqKey="Papadimitriou V" first="Vassiliki" last="Papadimitriou">Vassiliki Papadimitriou</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-469482" status="VALID">          <orgName>National Hellenic Research Foundation [Athens]</orgName>
          <date type="start">2016-10-21</date>
          <desc>            <address>              <country key="GR"></country>
            </address>
          </desc>
        </hal:affiliation>
<country>Grèce</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.foodres.2013.08.010</idno>
<series><title level="j">Food Research International</title>
<idno type="ISSN">0963-9969</idno>
<imprint><date type="datePub">2013-12</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term> DLS</term>
<term> EPR</term>
<term> Gallic acid</term>
<term> SAXS</term>
<term> Squalene</term>
<term>O/w microemulsions</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Nanodispersions based on food grade biocompatible materials were developed and structurally characterized to be used as carriers of bioactive compounds with specific nutritional value. The main idea was to formulate concentrated solutions of specific food components at the nanoscale to be consumed either on their own or as integrating parts of classic foods, upon aqueous dilution. For this purpose microemulsions consisting of (R)-(+)-limonene/ethanol/Tween 40/water/propylene glycol were formulated in the presence and in the absence of squalene, gallic acid and octyl gallate. The limits of the single-phase region as described by pseudo-ternary phase diagrams were related to the nature of the food additive. The more extended monophasic region was obtained when octyl gallate was added in the system. Interfacial properties of the microemulsions were studied by electron paramagnetic resonance (EPR) spectroscopy employing the nitroxide spin probe 5-doxylstearic acid (5-DSA). In general guest molecules decreased the flexibility of the surfactant monolayer as manifested from the calculation of rotational correlation time (T-R) and order parameter S of 5-DSA. Particle size measurements were performed using dynamic light scattering (DLS) and oil droplet diameters in the range of 11.7 to 17.4 nm were observed. The addition of squalene resulted in the formulation of larger oily droplets whereas octyl gallate formed smaller ones. Finally SAXS experiments provided qualitative information of o/w microemulsions showing squalene solubilization in the dispersed oily phase, octyl gallate localization on the membrane and gallic acid solubilization in the continuous aqueous phase.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
<li>Grèce</li>
</country>
<region><li>Grand Est</li>
<li>Lorraine (région)</li>
</region>
<settlement><li>Metz</li>
<li>Nancy</li>
</settlement>
<orgName><li>Université de Lorraine</li>
</orgName>
</list>
<tree><country name="Grèce"><noRegion><name sortKey="Kalaitzaki, Argyro" sort="Kalaitzaki, Argyro" uniqKey="Kalaitzaki A" first="Argyro" last="Kalaitzaki">Argyro Kalaitzaki</name>
</noRegion>
<name sortKey="Papadimitriou, Vassiliki" sort="Papadimitriou, Vassiliki" uniqKey="Papadimitriou V" first="Vassiliki" last="Papadimitriou">Vassiliki Papadimitriou</name>
<name sortKey="Xenakis, Aristotelis" sort="Xenakis, Aristotelis" uniqKey="Xenakis A" first="Aristotelis" last="Xenakis">Aristotelis Xenakis</name>
</country>
<country name="France"><region name="Grand Est"><name sortKey="Emo, Melanie" sort="Emo, Melanie" uniqKey="Emo M" first="Melanie" last="Emo">Melanie Emo</name>
</region>
<name sortKey="Stebe, Marie Jose" sort="Stebe, Marie Jose" uniqKey="Stebe M" first="Marie José" last="Stebe">Marie José Stebe</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/XenakisV1/Data/France/Analysis

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000016 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000016 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Musique
   |area=    XenakisV1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     Hal:hal-01493933
   |texte=   Biocompatible nanodispersions as delivery systems of food additives: A structural study
}}

This area was generated with Dilib version V0.6.33.
Data generation: Thu Nov 8 16:12:13 2018. Site generation: Wed Mar 6 22:10:31 2024

	Serveur d'exploration Xenakis
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Xenakis

Biocompatible nanodispersions as delivery systems of food additives: A structural study

Biocompatible nanodispersions as delivery systems of food additives: A structural study

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri